刚下了avastin官网的用药指南:
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Patients should continue treatment until disease progression or unacceptable toxicity. ' `5 |) @% Z& s$ [
1 Metastatic Colorectal Cancer (mCRC)
) H5 _, [: Y! p The recommended doses are 5 mg/kg or 10 mg/kg every 2 weeks when used in combination with + }) l6 m& b! }" Q% O
intravenous 5-FU-based chemotherapy.
$ v5 R9 y1 y$ \; j l% i' c• Administer 5 mg/kg when used in combination with bolus-IFL.
$ p& ]( H& P7 A, X: N: n• Administer 10 mg/kg when used in combination with FOLFOX4.
6 }, p3 B9 w* }9 e+ Q7 E2 Non-Squamous Non-Small Cell Lung Cancer (NSCLC)
" D1 A/ j, e. ?! A' J0 ^0 X H% v# J The recommended dose is 15 mg/kg every 3 weeks in combination with carboplatin and 4 }! N, L; U8 t* Y
paclitaxel. 3 u6 ^, V2 o7 N& d6 z3 }8 q
3 Metastatic Breast Cancer (MBC)
. G q K9 G# L! d( Z1 q7 @% @ The recommended dose is 10 mg/kg every 2 weeks in combination with paclitaxel.
: G& @7 P9 c3 F- {4 Glioblastoma: b1 A' q, a" N
The recommended dose is 10 mg/kg every 2 weeks.
6 c- S3 r/ ?: ]6 i- V5 r5 [5 w) U5 Metastatic Renal Cell Carcinoma (mRCC)( j' k* U/ }, v s" ^
The recommended dose is 10 mg/kg every 2 weeks in combination with interferon alfa.
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* y/ O, J% Q. |5 E( R7 Q" t按照这个说明非小细胞腺癌的服用剂量是15mg/kg,与卡铂紫杉醇合用,avastin每三周用一次。
4 s6 p' V) ]* }% F2 n% }我妈妈是肺腺癌转肝,体重53kg,现在医生联合卡铂紫杉醇化疗了一个疗程21天。 但avastin不是一次注射的,每7天注射一次200mg,一个疗程21天注射了3次(分别是第一、八、十五天) |